HORDB

ID: hor005841
Uniprot ID: Q16998
Protein name: LWamide I
Gene name: NA
Organism: Actinia equina (Beadlet anemone)
Family: LWamide neuropeptide family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Actinia (genus), Actiniidae (family), Actiniaria (order), Hexacorallia (subclass), Anthozoa (class), Cnidaria (phylum), Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: QHGLW
Length: 5
Propeptide: RSADAQQHGLWGKRQNPGLWGRSADAQQHGLWGKRQNPGLWGRSAEPGQPGLWGKRQNPGLWGRSAEPLQPGLWGKRQNPGLWGRSADAQQPGLWGKRQDLDIGMWGKRQKAGLWGRSADPGQLGLWGKRRSRIGLWGRSYEPPQFEDLEDLKKKSAIPKPSEQ
Signal peptide: NA
Modification: T5 Tryptophan amide
Glycosylation: NA
Mutagenesis: NA

Function: Metamorphosin A may be part of an internal signaling system involved in control of metamorphosis.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005841_AF2.pdb

hor005841_ESM.pdb

Mass:	71125	Formula:	C30H41N9O7
Absent amino acids:	ACDEFIKMNPRSTVY	Common amino acids:	GHLQW
pI:	7.55	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	2
Hydrophobicity:	-84	Boman Index:	-201
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	78
Instability Index:	3462	Extinction Coefficient cystines:	5500
Absorbance 280nm:	1375